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American Journal of Respiratory and Critical Care Medicine
The most innovative science and highest quality reviews, practice guidelines, and statements in pulmonary, critical care, and sleep-related fields.
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Significant and original observations in the area of pulmonary biology. Some focuses include cellular, biochemical, molecular, developmental, genetic, and immunologic studies of lung cells and molecules.
Annals of the American Thoracic Society
Up-to-date and authoritative coverage of adult and pediatric pulmonary and respiratory sleep medicine and adult medical critical care.
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Special ATS 2019 Conference Issue
The American Journal of Respiratory and Critical Care Medicine (AJRCCM) is planning a special issue to be distributed at the ATS 2019 International Conference, May 17 鈥 May 22, in Dallas.
November 9, 2018
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Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma
This study to reports independent associations between exposures to nitrogen dioxide, sulfur dioxide, carbon monoxide, and particulate matter less than or equal to 2.5 渭m in aerodynamic diameter and ARDS risk, and validates previous findings of an association between exposure to ozone and ARDS. The average exposures largely fell below current U.S. Environmental Protection Agency and European Union air quality standards.
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Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation鈥揇riven Airway Remodeling
The authors conclude that 1) BRD4 is a central effector of the mesenchymal transition that results in paracrine activation of myofibroblasts, and 2) highly selective BRD4 inhibitors may be effective in reversing the effects of repetitive airway viral infections on innate inflammation鈥搈ediated remodeling.
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Summary for Clinicians: Clinical Practice Guideline for Management of Malignant Pleural Effusions
The American Thoracic Society, Society of Thoracic Surgeons, and Society of Thoracic Radiology published clinical practice guidelines for the management of MPEs. The recommendations were based on systematic review of the clinical evidence and developed by a multidisciplinary panel of experts using the Grading of Recommendations, Assessment, Development, and Evaluation approach and the Evidence to Decision framework.
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Arterial Pulse Pressure Variation with Mechanical Ventilation
In medical critically ill patients, although no randomized controlled trial has compared PPV-based fluid management with standard care, the Surviving Sepsis Campaign guidelines recommend using fluid responsiveness indices, including PPV, whenever applicable. PPV is useful for managing fluid therapy under specific conditions where it is reliable. The kinetics of PPV during diagnostic or therapeutic tests is also helpful for fluid management.
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An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management
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Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
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Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline
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